Vitamin C Serum Scale-Up for a D2C Brand

India & Gulf export · Cosmetic & Personal Care Brands

Overview

Scale-up of an ascorbic acid serum from a 5 kg bench formulation to 1,200 kg batches, solving the discolouration that had failed the brand's first market trial.

The challenge

The brand's contract-developed serum turned amber within six weeks on shelf. Consumer returns in the first launch window were 11%, and photostability had never been run.

What we did

Reformulation moved to an ethylated ascorbic acid derivative with ferulic acid and a chelator, at a lower pH window, filled into airless pumps under nitrogen purge. Photostability per ICH Q1B confirmed the protected pack held colour; the exposed control did not, which settled the packaging argument with data.

Project data

Batch size5 kg bench → 1,200 kg production
Colour stabilityAmber at 6 weeks → stable at 12 months real time
Returns in launch window11% → under 1%
PhotostabilityICH Q1B run; airless pack required
PETISO 11930 criteria A met
Development to first commercial batch14 weeks

Standards applied

Scope supplied

Related

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